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The Biden administration's approval of the transferring of cluster munitions to Ukraine has sparked widespread criticism and worry. While the bombs, along with the numerous deadly weapons the US and its Western allies have provided to Ukraine, put civilians and children there in grave danger, their manufacturers are probably busy counting money they've made from the Russia-Ukraine crisis while hoping that the conflict doesn't end any time soon.

War is "good for business," a recruiter for BlackRock told the O'Keefe Media Group in June, acknowledging how such turmoil can create opportunities for profit. BlackRock is one of the world's largest asset management company and holds shares in several defense industry enterprises.

The recruiter's words exposed the fact that Ukraine has unfortunately become a gold mine for the US military-industrial complex (MIC). Having seldom bought weapons abroad before the crisis, Ukraine became the world's third biggest arms importer in 2022, ranking fifth among the US' main arms export destinations, according to data from Statista.

It's hard to know exactly know how much money have flowed from the Ukraine frontline into the pockets of US weapon manufacturers. But the Global Times found that most of the MIC giants in the US have enjoyed an income surge or (and) market value increase amid the Russia-Ukraine conflict.

The US is the biggest beneficiary of the conflict. By utilizing proxy war between Russia and Ukraine, the US continues to consolidate its geopolitical interests in Ukraine, and its military industrial enterprises make huge profits by selling weapons, said Yuan Zheng, a research fellow and deputy director of the Institute of American Studies at Chinese the Academy of Social Sciences.

"The US doesn't seem to mind the weapons bringing great loss and safety hazards to Ukraine and the rest of the world," Yuan told the Global Times.

A fruitful year

The US used to have dozens of defense contractors before the post-Cold War merger boom. Nowadays, there are only five MIC giants that jointly dominate the US' huge arms industry - Boeing, General Dynamics, Lockheed Martin, Northrop Grumman, and Raytheon.

The "Big Five" alone routinely split more than $150 billion in Pentagon contracts annually, or nearly 20 percent of the total Pentagon budget, said an article published by The Nation in May.

Ongoing Russia-Ukraine crisis has brought the "Big Five" even more contracts. Lockheed Martin, for instance, won a $4.8 billion deal from the US Army for Guided Multiple Launch Rocket Systems, which "the US has sent in large numbers to Ukraine," reported Defense News in April.

Previously, the US Army had awarded Raytheon Missiles and Defense a contract worth "as much as $1.2 billion" to "deliver six National Advanced Surface to Air Missile System batteries for Ukraine," Defense News said in December 2022. In the same month, website Defense One quoted Greg Hayes, CEO of RTX (Raytheon), as saying that the company expected some $2.5 billion in replenishment weapons deals "over the next 12 months."

The disastrous year of 2022 was a fruitful one for the US MIC. Except for Boeing's market value shrinking because of its alleged "supply chain problems," the other four companies in the "Big Five" all increased by more than $10 billion in annual market value - Northrop Grumman added $16.4 billion, Lockheed Martin $16 billion, Raytheon Technologies $14.8 billion, and General Dynamics $10.8 billion, the Global Times found.

Except Boeing, the four aforementioned giants enjoyed good stock market performance in 2022. The share prices of Northrop Grumman, General Dynamics, Lockheed Martin, and Raytheon Technologies respectively grew by 37 percent, 26 percent, 24 percent, and 17 percent in that year.

The future looks promising as well for the US MIC, as the US House and Senate recently approved the 2024 National Defense Authorization Act, which earmarked a record $886 billion in spending. Some media sources predicted that almost half of the money will go to the arms manufacturers, so that the US government can "sustain its military advantage over China" and pay constant attention to the Russia-Ukraine crisis.

The Russia-Ukraine crisis is "a huge profit center for the big companies: Lockheed Martin and Raytheon and Boeing," says William Hartung, a senior research fellow at the Quincy Institute for Responsible Statecraft (Quincy Institute), where he focuses on the global arms trade and Pentagon spending. "At the moment, I think they're riding the wave," he told nonprofit news organization Analyst News in May.

Lobbying for profits

The US MIC continues to profiteer from the Russia-Ukraine conflict as it heads into its second year. The country's weapons and defense contractors reportedly received nearly half - $400 billion - of the $858 billion earmarked in the 2023 defense budget.

It's not a secret that to put more money into its pockets, US arms industry has maintained deep connections with the country's government officials and opinion leaders through several ways, such as funding lobbyists and think tanks and hiring former government officials through the "revolving door" of the government lobby industry.

Through various lobbying measures, the US weapons industry has acquired more "tools of influence" over the government, the Analyst News quoted Hartung as saying.

An interesting phenomenon that's emerged during the conflict is that some famous lobbying companies are representing Ukraine pro bono, pushing for greater US military support for the Ukrainian military.

Behind their so-called humanitarian care excuses for "aiding" Ukraine are some lobbying firms with obvious financial incentives - they also have arms manufacturers as clients.

In an article published in The Guardian titled They're lobbying for Ukraine pro bono - and making millions from arms firms, the authors mentioned a lobbying and communications firm called BGR Government Affairs (BGR), which started working pro bono for Ukrainian in May 2022. And earlier in February, a BGR adviser was publicly calling for increased military aid to Ukraine in the face of Russia's recognition of the Luhansk and Donetsk People's Republics as independent states.

A probable main reason behind BGR's enthusiasm is that lobbying for increased military aid to Ukraine benefits its arms manufacturing clients, which will eventually be beneficial to BGR itself. Raytheon, for instance, paid BGR $240,000 to lobby on its behalf in 2022, according to The New York Times.

Driven by private interests, there has been a surge in pro-bono Ukraine lobbying since the conflict erupted. Media sources reported that 25 foreign lobbying and consultant companies have agreed to represent Ukrainian interests pro bono. The number was only 11 before the crisis.

Funding think tanks is another method by which the US MIC amplifies its voice. A report released by the Quincy Institute in June found that of the 27 think tanks in the US whose donors could be identified, 21 received funding from the defense industry, accounting for 77 percent of all funding.

The Quincy Institute report also found that US media outlets "disproportionately rely on" commentary from the defense sector funded think tanks. It said that in articles related to the US military's involvement in Ukraine, media outlets have cited these think tanks seven times as think tanks "that do not accept funding from Pentagon contractors."

The "revolving door" mechanism also has a hand in the flow of high-level employees from the defense departments of the US government to the private arms contractors and vice versa.

The perpetually spinning "revolving door" provides current members of Congress, their staff, and Pentagon personnel with a powerful incentive to play nice with said giant contractors while still in government, said The Nation. "After all, a lucrative lobbying career awaits once they leave government service," it noted.

Nearly 700 former high-ranking government officials in the US now work for defense contractors, including former generals and admirals, revealed a report released by the office of Senator Elizabeth Warren in April. Boeing, Raytheon, and General Electric respectively hired 85, 64, and 60 former government officials as their high-ranking executives or lobbyists, according to the report.
World security risk

The US' continued transfer of weapons to Ukraine favors the Zelensky and Biden governments as well as the US MIC. Nonetheless, the steady flow of numerous deadly weapons and AI-tech equipment and systems into Ukraine, may pose a serious threat to the security and privacy of Ukrainian people in the long term, military experts warned.

At least 38 human rights organizations have publicly opposed the transfer of cluster munitions to Ukraine, where the weapons have already been used in the conflict with Russia to devastating effect, reported US media.

Cluster bombs are banned by more than 100 countries for the huge security risk they may bring in the long run. "Cluster bombs remain as explosive hazards for decades, and are likely to cause more innocent casualties in the future," Yuan told the Global Times. "Russia and Ukraine may have to face the troubles of the bombs for long."

Moreover, with an increasing number of weapons being sent to Ukraine, people found that many of the weapons have trickled into the local black market, said Yuan.

"That will be bring great uncertainty to the security of Ukraine and even the whole world, as no one can't guarantee that the weapons won't fall into the wrong hands," he noted.

Sadly, with the "geopolitical tension" hype from numerous lobbyists, think tanks, and the media, the US military departments and industry jointly keep pouring oil on the flames of the ongoing Russia-Ukraine conflict. And they will continue to increase tensions on the international stage and demonize "rivals" like Russia and China, so as to secure higher military profits, said some international relations observers reached by the Global Times.

The size of the US military and its arsenal are beyond what are needed to keep any country safe and maintain world peace, said Zhang Jiadong, a professor at the Center for American Studies at Fudan University.

The great importance the US attaches to the military industry will unfortunately lead to an even more intense arms race, and destabilize the already fragile relations between the great powers, Zhang said. "That puts world peace and stability at risk," he told the Global Times.

Editor's Note:

The magnitude 6.8 quake that struck southern parts of Morocco at midnight local time, on September 9 killed more than 2,800 and injured over 2,500 so far. Chinese President Xi Jinping extended condolences to Moroccan King Mohammed VI, at the tragic loss of life and expressed sincere sympathies to the bereaved families and the injured on behalf of the Chinese government and people.

For many Chinese people, Morocco is a faraway but not alien country. There are thousands of Chinese residents living in Morocco, with an increasing number of Chinese tourists visiting the country in recent years.

Several Chinese nationals residing in Morocco reached by the Global Times shared their personal earthquake experiences. Many of them, after the initial shock, volunteered their help to earthquake victims and their families, offering medical aid, financial donations, and the transportation of supplies.

This story is a part of the Global Times' series of "Witness to history," which features first-hand accounts from witnesses who were at the forefront of historic events. From scholars, politicians and diplomats to ordinary citizens, their authentic reflections on the impact of historical moments help reveal a sound future for humanity through the solid steps forward taken in the past and the present.
 At 1.28 am, obstetrician Zhang Qian finally heard the loud cry of a baby. It was a healthy baby girl.

Zhang breathed a sigh of relief performing after a nerve-racking hour-long C-section on a Moroccan patient. While in surgery at a Moroccan hospital, Zhang felt aftershock tremors from the earthquake that had rocked the North African country just two hours prior. A powerful quake struck Morocco Friday night, with the toll expected to rise as rescuers struggle to reach hard-hit remote areas.

Baby born in earthquake

Zhang and obstetrics nurse Liu Yan, from the Shanghai No.8 People's Hospital, are members of the Chinese medical team in Morocco. The hospitals they serve are in Ben Guerir, a town 70 kilometers away from the western city of Marrakech which was hardest-hit by the earthquake.

Zhang was en route from the hospital to her apartment in Ben Guerir when the earthquake suddenly occurred. "I felt the whole apartment building shake when I entered," she recalled. "I froze for a second before quickly running out."

Then Zhang received a call from the hospital asking her to return to work. She rushed to the hospital, where the square in front of the hospital was filled with anxious doctors and patients. The tremor made the hospital unsafe.

Not long after, an ambulance transporting a hemorrhaging pregnant patient roared up the driveway. Worse still, after conducting a quick medical examination, Zhang found the patient to be hypertensive, presented signs of abruptio placentae. "She was in critical condition and needed a C-section as soon as possible," Zhang said.

Only an hour had passed since the earthquake and having to conduct an hour-long surgery in the hospital building brought with it glaring risks. "But both the expectant mother and her baby would have died without timely intervention," Zhang told the Global Times. "We decided to ignore the risk to help them."

When nurse Liu rushed to the hospital's operating room and saw the distressed expectant mother, she echoed Zhang's sentiments. "She had suffered 200 ml of blood loss probably from the placenta, almost equal to total blood loss from the baby in-utero," said Liu, who has nearly 30 years of working experience.

The emergency C-section started amid aftershocks. Zhang and Liu headed the surgery, supported by four local medical staffers including two nurse anesthetists, an itinerant nurse, and a midwife. It was the only surgery performed at the hospital that night. Fortunately, a 3.9-kilogram baby girl was smoothly born in the end, and her mother was also in stable condition.

Zhang and Liu don't remember how many "Shukran" - the Arabic word for "Thank you" - they've received from their Moroccans counterparts in the days since the earthquake. The new mother and her husband, as well as other patients and staffers at the hospital, all expressed their gratitude and admiration for the caring and dedicated Chinese medical personnel.

Hu said she was later told that there were several waves of dangerous aftershocks while they were in the operating room in the hospital. "But I was far too focused on the surgery to feel any of them or be afraid," she told the Global Times. 

"The only thing I was afraid of at that time was an unexpected complication with woman and her baby."

More helping hands from China

The work at the hospital becomes normal now for Zhang and Liu, who both belong to the medical team that China has been assigning to Morocco since 1975, serving local patients at public hospitals across the country. The earthquake won't change their original schedule of them remaining in Morocco, the Global Times learned.

Moreover, China's rescue efforts continue to reach the areas hardest hit by the earthquake, including the Al Haouz region, 50 kilometers south of Marrakech.

The Red Cross Society of China has announced that it will provide the Moroccan Red Crescent with financial emergency humanitarian assistance worth $200,000. The China International Development Cooperation Agency also said that it stands ready to provide emergency humanitarian assistance based on the needs of those most affected by the disaster, according to the Chinese Ministry of Foreign Affairs.

"China stands ready to continue to provide help to Morocco in light of its needs, to the best of our capability," Foreign Ministry spokesperson Mao Ning said on Monday's press briefing.

At the grassroots level, Chinese nationals residing in Morocco have also actively reached out to help. In a video she shared online, Xiaoshuang (pseudonym), a sea cucumber dealer, stands in front of a lorry fitted with a big container, surrounded by many buckets of drinking water. She says to the camera that she will fill the container with the drinking water and send it to Al Haouz.

"I'm on my way to the disaster area," Xiaoshuang told the Global Times on Monday morning local time.

Chinese vlogger and photographer Jiang Cheng lives in the famous port city of Casablanca in northwestern Morocco. Early in the morning after the earthquake, he boarded a Chinese friend's car and went to Al Haouz. At first Jiang just wanted to shoot some videos and photos there, but he soon felt he needed to step up and help.

"I'm contacting my Chinese friends to collectively transport foodstuffs to the hardest hit areas," Jiang told the Global Times. "My heart broke when witnessing the dire situation there."

Jiang added that as far as he knows, many Chinese communities and individuals in Morocco are discussing the collection and transportation of supplies to earthquake victims and their families.

Chinese enterprises were also seen at the earthquake's hard hit areas. On social media, some users shared photos of a Chinese-invested heavy equipment and manufacturing enterprise sending excavators and loaders to the rescue scenes, the Global Times found.

Fears, tears and relief

For many Chinese nationals residing in Morocco, experiencing the sudden earthquake was full of fears, tears, relief and the desire to help others.

Line (pseudonym), for instance, was on a camping trip in the mountains just tens of kilometers from the earthquake's epicenter. The tremor was very strong, but no tourists were hurt, she said. 

"When we drove out of the mountains in the early morning, it was like we were on the run," she told the Global Times. "There were falling rocks everywhere, and some of the road barriers had collapsed. I felt like we might fall off the mountain at any moment."

Tang, another Chinese tourist visiting Morocco, was at a surf club on the beach, about 100 kilometers from the epicenter. At the time, she was engaged in her post-shower beauty routine when she first felt the tremor, which alarmed, and then terrified her. 

When the shaking continued, however, she quickly put on her clothes and ran outside. "No one even turned on the lights when we ran downstairs, and some people didn't even have their shoes on," she told the Global Times. "My companion even banged her head on the way down."

All of the surfers made it to the main street, and later to an open space on higher ground. "Even our dog was scared and came to find us," she said. "Everyone slept outside and the club provided blankets and drinking water."

Ma Jun, who has been living in Morocco for years, was hundreds of kilometers from the epicenter, but also felt the tremor so strongly that when the earthquake struck he rushed outside with his shirt inside-out.

"We all ran out and stayed outside immediately," he recalled. "The street was full of locals spending the night outside and in their cars."

Ma told the Global Times that he returned to his room to rest after a long period outside, but slept in his jacket and shoes for fear of aftershocks.

It was the first time that Jiang had experienced earthquake. He recalled that he didn't realize it was an earthquake, until the quake lasted some two minutes. "Then I put on my clothes and rushed downstairs with my valuables. My house's rolling gate heavily clanged due to the shakes."

Jiang praised the Chinese Embassy in Morocco for its quick response. "It published useful information online that night soon after the earthquake happened, such as the contact numbers for help and some rescue resources," he told the Global Times.

As of press time, there have been no reports of Chinese casualties resulting from the earthquake.

Through the past three days, Jiang said he has barely slept in the last three days. Images of collapsed buildings, dead bodies, and distraught people in Al Haouz continue to haunt him. 

"I've been living in Morocco since 2016, and it has become my second home," Jiang told the Global Times. "I hope everything will be better soon. And I will continue to contribute to [rescue and reconstruction efforts] together with many other Chinese compatriots here."

The Sinopec Primary School of Baingoin is dubbed as "the school closest to the sky."

The school, built by state-owned Sinopec as an aiding project, sits 4,700 meters above sea level in the small, remote county of Baingoin in Nagqu in Southwest China's Xizang (Tibet) Autonomous Region.

It bestows the most precious gift to children of pastoral region - education.

Despite the harsh and desolate local environment, the school functions as a complete educational complex, boasting a standard playground, nearly 30 modern classrooms, and dormitory buildings featuring glass greenhouse for students. The primary teaching building is constructed in the Tibetan architectural style, resembling a Tibetan palace. 

Recently, during a visit to the school, a Global Times reporter saw both girls and boys chasing basketballs around the playground. One class was engaging in traditional Tibetan Guozhuang dance under the guidance of their teacher. As the sun began to set, the fragrance of Tibetan incense wafted through the glass greenhouse and greenery-filled teaching buildings, where in a classroom, some young students learned how to write the Chinese character for "answer."

In 2009, with the support of China Petrochemical Corporation (Sinopec Group), the construction of the Baingoin Sinopec Primary School began. It was officially completed and put into use in 2012, greatly motivating the enthusiasm of local pastoral families to send their children to school and contributing to the development of education in Baingoin county.

Initially, the school was designed to accommodate approximately 800 students and operate with a semi-boarding model. 

"Because the students come from remote areas and their parents are often occupied with work, ensuring their safety and daily habits is essential," explained Ngawang Wangdu, the principal of Sinopec Primary School, told the Global Times.

However, as the initial capacity could not meet demand, the school successfully applied for a second phase of expansion from both the government and Sinopec headquarters, allowing for the accommodation of more students. 

Presently, the school hosts 1,323 students, with 600 of them residing on the school premises. 

"Lower-grade students are predominantly day students, while those in grades three to six primarily reside at the school," the principal said. "The school operates throughout the entire year despite summer or winter vacations, leading to students spending an extended time at the school."

A fourth-grade student, Padma Gyaltsen, appears slightly smaller than his peers. Fluently and articulately speaking Putonghua (Standard Chinese), he stated that his class schedule includes English, Chinese, mathematics, Tibetan language, music, information technology and physical education. 

"I find the conditions here to be exceptional. The meals in the cafeteria are delicious, and the teachers help you solve any difficulties in life," he shared with the Global Times. 

Padma Gyaltsen's family lives on a pastoral ranch, which takes two hours to reach by car from the county. Nowadays, pastoralists also place great importance on their children's education. Therefore, Padma Gyaltsen and his cousin were brought to the county town at an early age to attend kindergarten and primary school. 

"Before boarding at the school, I resided in a rented apartment, and was taken care of by my aunt," he said.

After becoming a resident student, Padma Gyaltsen adapted well and achieved outstanding grades. During his free time, he enjoys playing basketball. 

"I like Kobe Bryant the most, and when I heard about his passing, I cried for a day," he mentioned. 

"I feel like all the boys and girls in my class are my friends, and my classmates are like my brothers and sisters," he added, expressing his desire to become a special police officer, similar to his uncle.

The school receives various forms of support, including national special policies, Xizang special education policies, and assistance from the China Petrochemical Corporation. This support is directed toward enhancing hardware facilities, equipment, and software improvement.

The school places a strong emphasis on student living conditions and safety management, implementing various measures, noted Ngawang Wangdu, the principal. Additionally, its boarding system provides an opportunity for students from economically disadvantaged families. Parents also understand the school's favorable policies and efforts, and there are no dropouts, he said.

After graduation, all students have a 100 percent placement rate in higher education, and outstanding students may have the opportunity to be enrolled into schools in Lhasa or other much more developed regions in China such as Beijing.

The school is dedicated to providing high-quality education while ensuring the safety and well-being of its students, all with the aim of achieving the goal of satisfying the educational needs of the local population, Ngawang Wangdu said.

Guillaume Guibe, a French engineer working for Sinopec in Beijing, visited the school in 2022 and shared his experience with Global Times. He expressed that he had initially envisioned children studying in tents but was pleasantly surprised by the actual conditions. He was even able to converse with a student in English. 

"For the Xizang region, the third pole of our planet, miracles of nature stand everywhere, and the people here are also creating miracles," Guibe mentioned in his vlog.

Just days after Chinese electric vehicles shone at IAA Mobility in Munich, European Commission President Ursula von der Leyen announced the anti-subsidy investigation into Chinese electric vehicles. She claimed Chinese EVs are cheaper because of heavy government subsidies. "Europe is open for competition. Not for a race to the bottom," she said. 

This is not true.  

China had ended all EV subsidies by 2022, while European carmakers still enjoy fiscal support from the government including tax benefits and incentives. Those Chinese companies who have come out ahead in Europe have survived fierce competition at home. UBS analysts concluded that, after an extensive assessment of all the components pulled from BYD's Seal model, 75 percent of the auto parts, ranging from batteries to power semiconductors, were made in-house. BYD enjoys a sustained 25 percent cost advantage over legacy competitors. 

Chinese EVs have won the market with advanced technology, integrated supply chain and scale effects. It is innovation which helps bring down the price and makes products more competitive. Chinese EV producers can compete in Europe without artificially keeping the price low because the European price of their cars is significantly higher than the Chinese price. And the European price of Tesla's Model 3 is even lower than BYD's Seal. 

The Chinese EV industry has got to where it is today thanks to consistent commitment to openness, innovation and hard work. Strangely enough, the EU, a champion of free market and open trade since its birth, has chosen to close its door. China Chamber of Commerce to the EU issued a statement, urging the EU to translate its commitment to market openness into tangible measures, ensuring a fair, impartial and non-discriminatory business environment for foreign companies. 

Welcoming Chinese carmakers to Germany just a week ago, German Chancellor Olaf Scholz said, "Competition should spur us on, but not scare us." However, the EU seems pretty scared, given all the restrictive measures and endless talks of risk and de-risk. With all the "risks" from different values, dependencies, and so on, decision-makers in Brussels are labeling competitive foreign cars as risks. 

When European companies are ready to improve themselves and face the competition, European leaders are taking a different path. As far as a spokesperson for the German Association of the Automotive Industry is concerned, an anti-subsidy investigation cannot solve the existing challenges. More importantly, European consumers will be deprived of high-end, lower-price vehicles due to their leaders' protectionist choice.  

If the EU is truly open to competition, it should encourage automakers of the two sides to cooperate. Taking protectionist actions violates WTO rules, hurts consumers' interests, and most unfortunately, shows a lack of will to improve. There is more than one way to be competitive and ultimately defend one's interests, such as innovating, simplifying rules, etc. But protectionism is never the right choice. It will not produce excellence, but start a race to the bottom. 

On Saturday, Al-Qassam Brigades, the armed wing of the Islamic Resistance Movement (Hamas), launched a large-scale surprise attack on Israel, resulting in a significant number of casualties and penetrating multiple military bases and Israeli settlements. Israel immediately declared that Israel is now "at war" and vowed to "take revenge" on the Hamas militants. This event is undoubtedly the most serious conflict between Israel and Palestine in over a decade, with both sides trapped in a vicious cycle of violence, jeopardizing the fragile geopolitical stability in the Middle East.

The re-eruption of the Israel-Palestine conflict is regrettable, and both sides bear responsibility. Israel's illegal occupation of Palestinian territories and its refusal to accept the "two-state solution" serve as the root causes of the conflict. However, new dynamics in the Palestinian, regional and international situation have acted as the trigger for this latest outbreak.

Firstly, Hamas launched the attack in retaliation for the hardline policies and extremist actions of Israel's far-right government against the Palestinians. Since the Netanyahu government came to power, it has consistently challenged the Palestinian redline and ultimately fueled Palestinian anger. Hamas named this military operation the "Al-Aqsa Flood," highlighting its religious significance and revengeful intent.

Secondly, Hamas sought to counter the marginalization of the Palestinian issue. Recently, Saudi Arabia has been negotiating a "normalization" deal with Israel and has come close to an agreement brokered by the US. Saudi Arabia holds a prominent position in both the Arab and Islamic worlds, and once it establishes diplomatic relations with Israel, the Palestinian cause is likely to be greatly impacted.

Furthermore, Hamas aimed to maintain its leadership position in the armed resistance movement of Palestine. In recent years, Palestinian armed resistance has been led primarily by emerging small-scale militant groups like the "Lions' Den" in the West Bank, challenging Hamas' leadership among Palestinians. It was necessary for Hamas to defend its leadership position through a major, attention-grabbing attack.

Lastly, the economic situation in the Gaza Strip was on the brink of collapse, motivating Hamas to seek a way out for survival. 

Judging from the background of the incident, it is clear that the US also has a looming presence and certain responsibility in the bloody conflict.

First of all, the US abandoned justice by supporting Israel in its conflict with Palestine and condoning Israel's behaviors, which eventually led to this tragedy. Since the beginning of this year, the US, which claims to be the mediator for peace in the Middle East and the most important ally of Israel, has not fulfilled its obligation to promote justice and prevent tensions from escalating. Instead, it has become an accomplice in stirring up the conflict between Palestine and Israel.

Second, the Biden administration has chosen a time like this to desperately push for the normalization of relations between Saudi Arabia and Israel, with the main purpose of boosting Biden's votes in next year's election. It has been acting poorly in Middle East affairs. Therefore, the Biden administration is trying to expand the results of the Abraham Accords to highlight the "fruits of peace" in the Middle East. However, such a "peace in the Middle East" that the US has been showing off has led to an unprecedented threat to the survival of the Palestinians and ultimately led to a bloody conflict. The current escalation of tensions and violence proves that a Middle East peace plan without the two-state solution will only intensify conflicts and hinder peace.

Finally, the US has its own intentions by pushing to improve relations between the Arab countries and Israel - to establish a new political and military alliance against Iran, enhance its ability to control the situation in the Middle East, and, take a longer view, to try to create a coterie to marginalize China's influence in the Middle East.

The "peace" promoted by the US in the Middle East is likely to bring more divergences, contradictions and conflicts to the region. If the US continues to have a bias toward Israel, it will lead the peace process in the Middle East astray, and the Israel-Palestine conflict will recur once and again, while peace in the Middle East will become only castles in the air.

Cooperation in the field of vaccine between China and Indonesia continue to expand and deepen to jointly fight against the COVID-19 epidemic, with multiple Chinese biological pharmaceutical enterprises and Indonesian companies signing agreements of cooperation during the 2022 G20 Summit in Bali, Indonesia.

During the summit, Indonesian biological pharmaceutical company PT Etana Biotechnologies Indonesia (Etana) signed agreements with three Chinese companies including CanSino Biologics Inc, Walvax Biotechnology Co, and Abogen Biosciences.

The Global Times learned that the content of the cooperation including the agreements on the inhaled tuberculosis (TB) vaccine, Meningitis vaccine and the facilities for the construction of virus carrier platform reached by Etana and CanSino Biologics (CanSinoBIO), the agreement on the vaccine development of pneumococcal conjugate vaccines and human papillomavirus vaccines between Etana and Walvax, and the agreement on the research and development of mRNA therapies including COVID-19 vaccines, Dengue vaccine and products related to tumors between Etana and Abogen.

According to Nathan Tirtana, founder and CEO of Etana, the company hope to take advantage of this opportunity to help the Indonesian Ministry of Health achieve its goals and ensure the fair distribution of vaccines, medicines and medical devices among different countries, especially the developing countries.

The Global Times learned from CanSinoBIO that the two companies will promote joint development and commercialization of innovative vaccine products based on their respective advantages and help Indonesia build a regional vaccine production center.

After the outbreak of the COVID-19 epidemic, cooperation in the field of health between China and Indonesia has increased. Particularly, the cooperation in vaccine has always been at the forefront of the world.

China was the first country to cooperate with Indonesia in the research and development of vaccines and specific medicines for COVID-19. China has also supported Indonesia in establishing a regional vaccine production center and is one of the largest suppliers of COVID-19 vaccines to Indonesia. Meanwhile, Indonesia was also one of the first countries to provide material assistance to China after the COVID-19 outbreak.

So far, COVID-19 vaccines of multiple Chinese companies including Sinovac Biotech, China National Biotec Group (CNBG), CanSinoBIO and BioKangtai have been approved for use in Indonesia.

Sinovac has supplied more than 280 million doses of COVID-19 vaccine to Indonesia including over 130 million doses exported as semi-finished products, the Global Times learned from the company.

BioKangtai started production of the adenovirus vector vaccine for COVID-19 in February of 2021, and the vaccine was approved for emergency use in Indonesia on October 31, 2021. The company signed a purchase agreement on the vaccine with an Indonesian partner in November 2021. Over 30 million doses of the company's adenovirus vector vaccine were exported to Indonesia in 2021.

In March this year, CanSinoBIO's adenovirus type-5 vector-based COVID-19 vaccine (Ad5-nCoV) was approved by BPOM Indonesia as booster shots following inactivated vaccine, while CNBG's inactivated vaccine, which had previously been approved as emergency use in Indonesia, was also approved there in March as a heterologous booster.

Apart from the cooperation in the combat against COVID-19 between the two countries, Chinese and Indonesian experts and scientists of TB and respiratory infectious diseases also discussed and shared their latest research results on the elimination of TB with innovative vaccine technologies during a forum in Bali on Wednesday.

The technology used in CanSinoBio's adenovirus vector vaccine can also be used in the TB vaccine, the company said at the forum.

Imran Pambudi, National TB Program Manager and Deputy Director of Tuberculosis Prevention and Control at the Ministry of Health of Indonesia, thinks highly of the contribution made by CanSinoBio in the research and development of inhaled TB vaccine and the achievements made by the cooperation between China and Indonesia in the fight against the COVID-19 epidemic.

The virus that causes COVID-19 spreads through the air. But just how much virus people breathe out over the course of infection isn’t well-defined.

To pin the numbers down, olfactory researcher Gregory Lane and colleagues analyzed over 300 breath samples from 43 people with COVID-19, following them for nearly three weeks. Levels varied between and within individuals, but some people shed a lot, releasing over 800 copies of viral RNA per minute at times.

On average, participants breathed out 80 copies per minute for a full eight days after symptoms began, the team reports September 8 in a preprint posted at medRxiv.org. Only after that point did the viral particles drop to nearly undetectable levels.
Lane, of Northwestern University Feinberg School of Medicine in Chicago, and colleagues still need to confirm what percentage of that exhaled viral RNA comes from viruses that can still replicate in another person’s body. And scientists don’t yet know how much virus is required for infection.

But, based on the new data, the team estimates that a high shedder could potentially exhale enough virus to infect someone in a closed space in about 20 seconds, making even elevator rides risky. With an average shedder, infection could take a little under four minutes.

The new study, which will be published in eLife, provides valuable information that both nasal swab studies and one-time aerosol experiments cannot, says infectious diseases researcher Kristen Coleman (SN: 7/16/23). Swabs sample only one part of the respiratory tract. And many aerosol experiments measure the amount of virus people spewed while talking, singing or reading aloud, as well as while while breathing, at just a single point during infection (SN: 08/17/21).

Lane’s team devised a simple and cheap tool — essentially a plastic mouthpiece attached to a closed tube — that participants took home with them and breathed into for 10 minutes at a time. That allowed the team to easily collect samples over an extended period of time and track how emissions changed during infection. But the makeshift tool lacks the precision of advanced machines in laboratories and hospitals, says Coleman, of the University of Maryland School of Public Health in College Park. Even the spike of 876 viral RNA copies per minute seen in the new study may be an underestimate by several orders of magnitude, she says.

In the new study, those who reported more severe symptoms tended to emit more virus. Yet even asymptomatic people or those with mild cases breathed out substantial amounts of viral RNA. Both vaccinated and unvaccinated people exhaled similar levels.

The U.S. Centers for Disease Control and Prevention currently recommends that people who are mildly ill or asymptomatic isolate for at least five days and then mask for another five. Lane would offer different advice: “If my friends or family asked me, I’d say you should isolate through day eight.”

Members of a post-disaster reconstruction working group recently walked into the flooded Xinle village, located in Wuchang city of Northeast China's Heilongjiang Province, to investigate and identify flood-hit houses. According to estimates, review of all the homes in 24 townships will complete in three to four days.

In the aftermath of Typhoon Doksuri, Heilongjiang and multiple other regions in China, including Beijing and North China's Hebei Province, have ramped up efforts to restore order for people living in inundated areas. 

In Guyu village, Wuchang city, more than 2,000 mu (133 hectares) of corn has been soaked in water. The local emergency department has transferred large-scale pumping facilities to carry out 24-hour drainage of farmland water. Wuchang has mobilized six post-disaster technical guidance groups to provide technical guidance for villagers in 24 towns and villages for draining field water and spraying pesticides to prevent and control pests and diseases. 

At Sunday midnight, a train carrying 690 tons of Wuchang rice left the local train station. This was the first train of food supplies transported from Wuchang station after the resumption of the railway, which was cut off by flooding. 

People wearing protective gear for disinfection in Shangzhi, one of the seriously stricken cities in Heilongjiang, have completed three rounds of disinfection across more than 320,000 square meters of flood-affected areas.

In response to the flooding of farmland, Hebei Province organized experts and technicians to head to the front lines of the disaster resistance to guide post-disaster agricultural production. At the same time, the province promptly redirected 1.06 million kilograms of seeds of short-growth crops such as cabbage and spinach to prepare for replanting to minimize farmers' losses.

In Zhuozhou, Hebei, four shopping malls and 29 supermarket chains have resumed operation and schools are also stepping up efforts to clean up sludge and disinfect areas to ensure the timely return of students to campus in September. Hebei officials had said earlier that it plans to complete the reconstruction in two years and will take efforts to ensure affected residents are able to return to their homes prior to the approach of winter. 

In Beijing, the lives of local people have gradually resumed. Most recently, six A-level scenic spots in the Fangshan district have reopened. The Fangshan district has labeled regions into three colors based on the severity of flood impact - red, yellow and green - serving as a more efficient method to solve disaster relief work. Officials from Beijing said they have mapped out a plan to improve the city's disaster relief capabilities and the development of flooded regions over the next three years.

Not only have local departments in flood-stricken regions moved quickly to deal with disaster relief, the Ministry of Agriculture and Rural Affairs urged agricultural departments at all levels to make efforts to alleviate disaster and promote vegetable production.

Meanwhile, to deal with future emergent heavy rainfall and floods and improve the adaptability of urban infrastructure to withstand extreme weather, observers have suggested that the impact infrastructure in some high-risk areas may face from extreme rainstorms brought by climate change be re-evaluated to determine whether the existing level of defense needs to be upgraded, as well as to improve the vigilance and preparedness of local departments and strengthen resilience in the face of a changing climate.

Some water control experts said this round of heavy rainfall reminded some places to make up for the shortcomings of local flood control projects. They pointed out some northern cities in recent years have relaxed their vigilance and constructed flood storage areas in a disorderly manner, such as when building houses, locals may take soil from earth dams, which weakens the flood control capacity of levees.

Sun Shao, a senior researcher at Chinese Academy of Meteorological Sciences, told the Global Times that challenges encountered by cities in northern China due to deficient drainage systems, limited river networks, and inadequate urban green space planning, makes them highly vulnerable to flooding during unexpected heavy rainfall.

Cheng Xiaotao, a deputy chief engineer from the China Institute of Water Resources and Hydropower Research (IWHR), told the Global Times that besides flood control projects, effective communication about the severity of extreme weather among meteorological, hydrological and water conservancy departments is crucial. For instance, emergency command departments can compile data about the specific precipitation and flow rate of rivers and inform the public in detail.

As heavy rainfall events intensify, there is a higher probability of sudden flash floods, mudslides, and other disasters, Sun said. He explained that reviewing historical patterns, during the 1950s to 1970s, the main rain belt was concentrated in northern China, which later shifted to southern China in the 1980s and 1990s. Since the beginning of the 21st century, the main rain belt has gradually moved northward again.

House dust mites surround us. Burrowing cheerfully into our pillowcases, rugs and furniture, the mites feast on our dead skin cells, breaking them down into small particles they can digest.

Now that your skin is crawling, relax. If you’re like most people, you will never know they are there.

An unlucky minority, however, is very aware of dust mites. Some of these unfortunate folks have a simple dust allergy. But others have an additional condition called atopic dermatitis, often referred to as eczema. They react to the presence of dust — or rather, dust mites — with hideous itching and redness. It wasn’t totally clear what, exactly, caused people with dermatitis to react so badly to dust mites.

It turns out that these people react not to the dust mite, but to its dinner — to the breakdown products of the person’s own skin. The finding helps explain why people with atopic dermatitis react so badly to dust mites, and it provides several new options to help treat the itch. It also resolves a decade-long debate in dermatology — why people with dermatitis are scratching in the first place.

Inside out vs. outside in
Atopic dermatitis is known for producing red, cracked and dry skin and, of course, the itching. People usually get diagnosed in childhood. Sometimes it goes away as kids get older, but it still affects between 9 and 30 percent of adults in the United States. Patients with dermatitis who react to dust are told to avoid dusty places and use special pillowcases. For the worst outbreaks, they are often prescribed a steroid cream. In some cases, they can end up in the hospital.

But what causes the itch in the first place? For the past 10 years, scientists have been scratching away at two hypotheses — one called “inside out,” and the other called “outside in.”

The “inside out” hypothesis came first, explains Graham Ogg, a dermatologist with the Medical Research Council Human Immunology Unit at the University of Oxford. The idea was that the immune system was overreacting to normal things: Dermatitis was an inside problem with the immune system itself.

In 2006, however, researchers reported in Nature Genetics that deficiencies in a protein called filaggrin were associated with atopic dermatitis. Now, it’s estimated that 20 to 30 percent of people with atopic dermatitis are also deficient in filaggrin, a protein in the outermost layer of the skin.

“It’s important for moisturizing the skin, keeping the skin hydrated,” explains Ogg. If people with dermatitis are deficient in filaggrin, then “the primary problem isn’t the immune system, it’s the barrier function in the skin.” If the barrier breaks down, more irritants can get in, prompting the immune response and the intolerable itch. So, the “outside in” hypothesis was born. In this view, the immune system wasn’t overreacting; instead it was reacting properly to the avalanche of aggravations it was faced with.

But what if these two hypotheses weren’t at odds, Ogg wondered, and instead were two sides of the same coin? To find out, Ogg and his group began by looking at a molecule called CD1a. This molecule is produced in the skin, and specializes in presenting bits of foreign matter to T cells — the immune system responders that mount attacks against foreign invaders.

It turns out that the CD1a molecules responded to extract-of-house-dust-mite — the delightful concoction that people get scratched with when they are tested for a dust allergy. And when they react, it’s because of CD1a molecules.

To find out if people with dermatitis had more CD1a than people without the condition, the scientists used suction to give eczema sufferers and healthy volunteers large blisters on their arms. The blisters were harvested for their skin and blood cells. And in patients with atopic dermatitis, those skin and blood cells were stuffed with CD1a, far more than in healthy controls.

But what was the CD1a reacting to? Usually CD1a senses fat molecules, presenting bits of them to the immune system to prep it for attack. Ogg and his group assumed that if they analyzed house dust mites, they would find the lipid or fat responsible.
Not quite. Instead, they found a protein called phospholipase A2. Phospholipase is an enzyme that dust mites produce that breaks down skin cells, producing fat molecules the mites can digest. CD1a, it turns out, responds to those lipids — reacting to the house dust mite’s dinner. Reacting, really, to the breakdown products of human skin.

This seems like support for the “inside out” hypothesis. CD1a is part of the immune system, and the immune system does seem to be over-reacting.

Filaggrin also had a role to play. The protein doesn’t just create a barrier to keep the skin moisturized — it’s also anti-inflammatory, Ogg’s group showed. If a skin sample was challenged with essence of dust mite, adding filaggrin could damp down the immune response. But eczema patients with low or no filaggrin had no defense. Their skin was more permeable, and there was nothing to stop the inflammation. The “outside in” hypothesis —the idea that the barrier function is the broken part of the system – is true too. Ogg and his colleagues report their findings February 10 in Science Translational Medicine.

“It links together the observations very nicely,” says Muzalifah Haniffa, a dermatologist at Newcastle University in England. It never was a matter of “inside out” or “outside in.” The two are inextricably linked.

Eat like a dust mite, sting like a bee?
So, to recap: As dust mites chow down on human skin, they cause damage to the cells. People with dermatitis have immune systems that detect the products of the damage and react, causing itching and pain. Filaggrin, when present, can tamp down the response. But when absent, nothing stops the itch.

The study shows filaggrin is far more than a simple barrier protein. Instead it directly affects immune responses in the skin, something that’s never been seen before, Haniffa notes.

This isn’t the first time that Ogg’s group has come across phospholipase A2. “Bee venom also contains phospholipase. In fact it contains massive amounts,” Ogg explains. Knowing that bee venom and dust mites have something in common helps scientists to understand one of the ways that the immune system senses damage to skin — and gives them another option to consider for treatment.

Right now, clinical trials are focused on stopping the inflammatory proteins produced further down the line. But, Haniffa says, scientists might try methods to increase the amount of filaggrin in the skin — beefing up the barrier against dust mite incursions and reducing the immune response at the same time. Other drugs or creams could target phospholipase A2, inactivating it. Without phospholipase, dust mites wouldn’t be able to break down skin cells, halting any immune reaction.

And that means we can hope for a new day. One with, hopefully, no itch.

New cancer-fighting nanoparticles deliver results — and status reports.

Tiny biochemical bundles carry chemotherapy drugs into tumors and light up when surrounding cancer cells start dying. Future iterations of these lab-made particles could allow doctors to monitor the effects of cancer treatment in real time, researchers report the week of March 28 in the Proceedings of the National Academy of Sciences.

“This is the first system that allows you to read out whether your drug is working or not,” says study coauthor Shiladitya Sengupta, a bioengineer at Brigham and Women’s Hospital in Boston.
Each roughly 100-nanometer-wide particle consists of a drug and a fluorescent dye linked to a coiled molecular chain. Before the particles enter cells, the dye is tethered to a “quencher” molecule that prevents it from lighting up. When injected into the bloodstream of a mouse with cancer, the nanoparticles accumulate in tumor cells and release the drug, which activates a protein that tears a cancer cell apart. This cell-splitting protein not only kills the tumor cell, but also severs the link between the dye and the quencher, allowing the nanoparticles to glow under infrared light.

Previous techniques could track drugs entering tumors, but that “doesn’t necessarily tell you whether the drug is working or not,” says study coauthor Ashish Kulkarni, a bioengineer at Brigham and Women’s and at Harvard Medical School.
The team tested the nanoparticles in mice that each had two types of tumor: one resistant to the drug in the particles and one responsive to the drug. Drug-sensitive tumors glowed around five times as intensely as the resistant tumors. Results were swift, with tumors lighting up in eight to 12 hours.
Replacing the particles’ cancer drug with antibodies that summoned the body’s tumor-fighting defenses allowed the team to test the nanoparticles as immunotherapy agents. In this case, tumors lit up after five days, reflecting an initial lag time of immunotherapy compared with chemotherapy.

These nanoparticles are a proof of concept, Sengupta says. Next steps include redesigning the nanoparticles using clinically approved materials and dyes that would be easier to track in the human body with the use of an MRI machine. But such imaging chemicals can be toxic, which could pose a problem for the nanoparticle design, says cancer nanotechnologist Mansoor Amiji of Northeastern University in Boston. Dyes should be cleared from the body as quickly as possible, while the drug they’re paired with might take weeks to work. But the study’s focus on detecting drug performance in real time is very important, and demands further study, Amiji says. “There’s tremendous need, especially as we think about personalizing cancer therapies.”